Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth X]Ins134_P3_kin_Ce1z2oX1 A: a+b complex topologyX: Protein kinase/SAICAR synthase/ATP-grasp (From Homology)H: Protein kinase/SAICAR synthase/ATP-graspT: ATP-graspF: Ins134_P3_kin_CECOD (1.6)
A [auth X]EUF08596e1z2oX3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: PreATP-grasp domainF: EUF08596ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A [auth X]3.40.50.10820 Alpha Beta 3-Layer(aba) Sandwich Rossmann fold Inositol 1,3,4-trisphosphate 5/6-kinase domainCATH (4.3.0)
A [auth X]3.30.470.20 Alpha Beta 2-Layer Sandwich D-amino Acid Aminotransferase Chain A, domain 1CATH (4.3.0)
A [auth X]3.30.1490.220 Alpha Beta 2-Layer Sandwich Dna Ligase domain 1CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth X]PF05770Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain (Ins134_P3_kin)Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domainThis family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphat ...This family consists of several inositol 1, 3, 4-trisphosphate 5/6-kinase proteins. Inositol 1,3,4-trisphosphate is at a branch point in inositol phosphate metabolism. It is dephosphorylated by specific phosphatases to either inositol 3,4-bisphosphate or inositol 1,3-bisphosphate. Alternatively, it is phosphorylated to inositol 1,3,4,6-tetrakisphosphate or inositol 1,3,4,5-tetrakisphosphate by inositol trisphosphate 5/6-kinase [1]. This entry represents the ATP-grasp domain.
Domain
A [auth X]PF21512Inositol-tetrakisphosphate 1-kinase, preATP-grasp domain (ITPK1_preATP-grasp)Inositol-tetrakisphosphate 1-kinase, preATP-grasp domainInositol-tetrakisphosphate 1-kinase (ITPK1) can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5 which may play a regulatory function. It may al ...Inositol-tetrakisphosphate 1-kinase (ITPK1) can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Phosphorylates Ins(3,4,5,6)P4 at position 1 to form Ins(1,3,4,5,6)P5 which may play a regulatory function. It may also act as an isomerase. This entry represents the preATP-grasp domain [1].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth X]inositol 1,3,4-trisphosphate 5/6-kinase -