2BVY

The structure and characterization of a modular endo-beta-1,4-mannanase from Cellulomonas fimi

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2bvya1	All beta proteins	Immunoglobulin-like beta-sandwich	E set domains	E-set domains of sugar-utilizing enzymes	Beta-1,4-mannanase domain 2 (postcatalytic)	(Cellulomonas fimi ) [TaxId: 1708 ],	SCOPe (2.08)
A	d2bvya2	Alpha and beta proteins (a/b)	TIM beta/alpha-barrel	(Trans)glycosidases	beta-glycanases	Mannanase A, ManA	(Cellulomonas fimi ) [TaxId: 1708 ],	SCOPe (2.08)
A	d2bvya3	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Cellulomonas fimi ) [TaxId: 1708 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	beta-glycanases	8026328	4003164	SCOP2 (2022-06-29)
A	SCOP2 Family	E-set domains of sugar-utilizing enzymes	8054954	4007565	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	(Trans)glycosidases	8038707	3000313	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	E set domains	8054955	3000070	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CopC_like	e2bvyA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: CopC_like	ECOD (1.6)
A	Glyco_hydro_26	e2bvyA2	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: Glyco_hydro_26	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.20.20.80	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Glycosidases	CATH (4.3.0)
A	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF02156	Glycosyl hydrolase family 26 (Glyco_hydro_26)	Glycosyl hydrolase family 26	-	Domain
A	PF17957	Bacterial Ig domain (Big_7)	Bacterial Ig domain	This entry represents a bacterial ig-like domain that is found in glycosyl hydrolase enzymes.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	BETA-1,4-MANNANASE	mannan endo-1,4-beta-mannosidase activity hydrolase activity, acting on glycosyl bonds beta-mannosidase activity hydrolase activity, hydrolyzing O-glycosyl compounds mannosidase activity hydrolase activity catalytic activity cellulase activity cation binding ion binding binding metal ion binding small molecule binding	carbohydrate metabolic process polysaccharide metabolic process substituted mannan metabolic process metabolic process cellular process primary metabolic process macromolecule metabolic process catabolic process glucan catabolic process beta-glucan metabolic process carbohydrate catabolic process macromolecule catabolic process glucan metabolic process beta-glucan catabolic process carbohydrate metabolic process polysaccharide metabolic process substituted mannan metabolic process metabolic process cellular process primary metabolic process macromolecule metabolic process catabolic process glucan catabolic process beta-glucan metabolic process carbohydrate catabolic process macromolecule catabolic process glucan metabolic process beta-glucan catabolic process polysaccharide catabolic process cellulose catabolic process cellulose metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR005087	Carbohydrate binding module family 11	Domain
A	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A	IPR008979	Galactose-binding-like domain superfamily	Homologous Superfamily
A	IPR001119	S-layer homology domain	Domain
A	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A	IPR014756	Immunoglobulin E-set	Homologous Superfamily
A	IPR022790	Glycosyl hydrolase family 26 domain	Domain
A	IPR000805	Glycoside hydrolase family 26	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.