Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilySARS coronavirus NSP10-like 8029117 4000543 SCOP2 (2022-06-29)
ASCOP2 SuperfamilySARS coronavirus NSP10-like 8041496 3000547 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ANSP10e2fygA1 A: few secondary structure elementsX: Coronavirus NSP10-like (From Topology)H: Coronavirus NSP10-like (From Topology)T: Coronavirus NSP10-likeF: NSP10ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF09401Coronavirus RNA synthesis protein NSP10 (CoV_NSP10)Coronavirus RNA synthesis protein NSP10- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Replicase polyprotein 1ab

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR022733DPUP/SUD, C-terminal, betacoronavirusDomain
IPR024358Non-structural protein NSP3, N-terminal, betacoronavirusDomain
IPR043611Coronavirus replicase NSP3, C-terminalDomain
IPR044864Non-structural protein NSP3, SUD-N (Mac2) domain, betacoronavirusDomain
IPR038123Non-structural protein NSP4, C-terminal superfamily, coronavirusHomologous Superfamily
IPR042570Non-structural protein NSP3, nucleic acid-binding domain superfamily, betacoronavirusHomologous Superfamily
IPR047566Coronavirus replicase NSP3, Y domainDomain
IPR043178Papain-like protease, thumb domain superfamily, coronavirusHomologous Superfamily
IPR043612Non-structural protein NSP4, N-terminal, coronavirusDomain
IPR038166Polyprotein cleavage domain PL2pro superfamily, betacoronavirusHomologous Superfamily
IPR044353NSP3, second ubiquitin-like (Ubl) domain, coronavirusDomain
IPR009003Peptidase S1, PA clanHomologous Superfamily
IPR013016Peptidase C16, coronavirusDomain
IPR037204Non-structural protein NSP7 superfamily, coronavirusHomologous Superfamily
IPR044374Non-structural protein 3, SUD-N macrodomain, SARS-CoVDomain
IPR044357NSP3, first ubiquitin-like (Ubl) domain, coronavirusDomain
IPR046443NSP1, globular domain, alpha/betacoronavirusDomain
IPR043610Non-structural protein 6, coronavirusDomain
IPR043477Peptidase C30, domain 3, coronavirusHomologous Superfamily
IPR018995RNA synthesis protein NSP10, coronavirusDomain
IPR043478Non-structural protein NSP3, SUD-N (Mac2) domain superfamily, betacoronavirusHomologous Superfamily
IPR038400Non-structural protein NSP3, SUD-M domain superfamily, betacoronavirusHomologous Superfamily
IPR046442NSP1, C-terminal domain, betacoronavirusDomain
IPR043615Nonstructural protein 2, N-terminal domain, coronavirusDomain
IPR043177Papain-like protease, N-terminal domain superfamily, coronavirusHomologous Superfamily
IPR014822Non-structural protein NSP9, coronavirusDomain
IPR038030NSP1 globular domain superfamily, betacoronavirusHomologous Superfamily
IPR021590NSP1, globular domain, betacoronavirusDomain
IPR024375Non-structural protein NSP3, SUD-M domain, betacoronavirusDomain
IPR044367Non-structural protein 6, betacoronavirusDomain
IPR037230Non-structural protein NSP8 superfamily, coronavirusHomologous Superfamily
IPR014828Non-structural protein NSP7, coronavirusDomain
IPR032505Non-structural protein NSP4, C-terminal, coronavirusDomain
IPR043503Papain-like viral protease, palm and finger domains, coronavirusHomologous Superfamily
IPR014829Non-structural protein NSP8, coronavirusDomain
IPR036499Non-structural protein NSP9 superfamily, coronavirusHomologous Superfamily
IPR002589Macro domainDomain
IPR047567Non-structural protein NSP3, group 2-specific marker domain, betacoronavirusDomain
IPR044389Non-structural protein 2, SARS-CoV-likeDomain
IPR008740Peptidase C30, coronavirusDomain
IPR036333RNA synthesis protein NSP10 superfamily, coronavirusHomologous Superfamily
IPR047573Non-structural protein 2, middle domain, coronavirusDomain
IPR049894Coronavirus NSP3, 3Ecto domainDomain
IPR043472Macro domain-likeHomologous Superfamily
IPR044371Non-structural protein 3, X-domain-likeDomain
IPR032592Non-structural protein NSP3, nucleic acid-binding domain, betacoronavirusDomain
IPR043613Non-structural protein 2, C-terminal domain, coronavirusDomain
IPR038083Non-structural protein NSP3A domain-like superfamilyHomologous Superfamily
IPR043504Peptidase S1, PA clan, chymotrypsin-like foldHomologous Superfamily