Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyFAD-linked oxidoreductase 8042722 3000663 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APro_dhe2fzmA5 A: a/b barrelsX: TIM beta/alpha-barrelH: TIM barrels (From Topology)T: TIM barrelsF: Pro_dhECOD (1.6)
AputA_2nd,Pro_dh-DNA_bdge2fzmA2 A: extended segmentsX: N-terminal domain of bifunctional PutA protein (From Topology)H: N-terminal domain of bifunctional PutA protein (From Topology)T: N-terminal domain of bifunctional PutA proteinF: putA_2nd,Pro_dh-DNA_bdgECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.20.20.220 Alpha Beta Alpha-Beta Barrel TIM Barrel CATH (4.3.0)
A1.20.5.460 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF01619Proline dehydrogenase (Pro_dh)Proline dehydrogenase- Family
PF18327Proline utilization A proline dehydrogenase N-terminal domain (PRODH)Proline utilization A proline dehydrogenase N-terminal domainThis is the N-terminal domain found in Proline utilization A (PutA) proteins. Proline utilization A (PutA) is a flavoprotein that has mutually exclusive roles as a transcriptional repressor of the put regulon and a membrane-associated enzyme that cat ...This is the N-terminal domain found in Proline utilization A (PutA) proteins. Proline utilization A (PutA) is a flavoprotein that has mutually exclusive roles as a transcriptional repressor of the put regulon and a membrane-associated enzyme that catalyzes the oxidation of proline to glutamate [4]. The N-terminal region carries the flavoenzyme proline dehydrogenase (PRODH) domain which catalyzes the 2-electron oxidation of proline with the concomitant reduction of a flavin cofactor [9].
Domain
PF14850DNA-binding domain of Proline dehydrogenase (Pro_dh-DNA_bdg)DNA-binding domain of Proline dehydrogenaseThis domain lies at the N-terminus of bifunctional proline-dehydrogenases and is found to bind DNA.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Bifunctional protein putA, Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase)