Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2gmja1 Alpha and beta proteins (a/b) FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain FAD-linked reductases, N-terminal domain Electron transfer flavoprotein-ubiquinone oxidoreductase, EFT-QO (Sus scrofa ) [TaxId: 9823 ], SCOPe (2.08)
Ad2gmja2 Alpha and beta proteins (a+b) FAD-linked reductases, C-terminal domain FAD-linked reductases, C-terminal domain Electron transfer flavoprotein-ubiquinone oxidoreductase-like Electron transfer flavoprotein-ubiquinone oxidoreductase, EFT-QO (Sus scrofa ) [TaxId: 9823 ], SCOPe (2.08)
Ad2gmja3 Alpha and beta proteins (a+b) Ferredoxin-like 4Fe-4S ferredoxins ETF-QO domain-like Electron transfer flavoprotein-ubiquinone oxidoreductase, EFT-QO (Sus scrofa ) [TaxId: 9823 ], SCOPe (2.08)
Bd2gmjb1 Alpha and beta proteins (a/b) FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain FAD-linked reductases, N-terminal domain Electron transfer flavoprotein-ubiquinone oxidoreductase, EFT-QO (Sus scrofa ) [TaxId: 9823 ], SCOPe (2.08)
Bd2gmjb2 Alpha and beta proteins (a+b) FAD-linked reductases, C-terminal domain FAD-linked reductases, C-terminal domain Electron transfer flavoprotein-ubiquinone oxidoreductase-like Electron transfer flavoprotein-ubiquinone oxidoreductase, EFT-QO (Sus scrofa ) [TaxId: 9823 ], SCOPe (2.08)
Bd2gmjb3 Alpha and beta proteins (a+b) Ferredoxin-like 4Fe-4S ferredoxins ETF-QO domain-like Electron transfer flavoprotein-ubiquinone oxidoreductase, EFT-QO (Sus scrofa ) [TaxId: 9823 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B Superfamily4Fe-4S ferredoxins 8001550 3000020 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyFlavoreductase-like 8001416 3000055 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyFlavoreductase-like 8001416 3000055 SCOP2B (2022-06-29)
BSCOP2B Superfamily4Fe-4S ferredoxins 8001550 3000020 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AETF_QOe2gmjA1 A: a+b two layersX: 4Fe-4S ferredoxin (From Topology)H: 4Fe-4S ferredoxin (From Topology)T: 4Fe-4S ferredoxinF: ETF_QOECOD (1.6)
AKOG2415e2gmjA2 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD-linked reductases-C (From Topology)T: FAD-linked reductases-CF: KOG2415ECOD (1.6)
AFAD_binding_3_1ste2gmjA3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: FAD_binding_3_1stECOD (1.6)
BETF_QOe2gmjB1 A: a+b two layersX: 4Fe-4S ferredoxin (From Topology)H: 4Fe-4S ferredoxin (From Topology)T: 4Fe-4S ferredoxinF: ETF_QOECOD (1.6)
BKOG2415e2gmjB2 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD-linked reductases-C (From Topology)T: FAD-linked reductases-CF: KOG2415ECOD (1.6)
BFAD_binding_3_1ste2gmjB3 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: FAD_binding_3_1stECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF21162ETF-QO, ubiquinone-binding (ETFQO_UQ-bd)ETF-QO, ubiquinone-bindingElectron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) is a a 4Fe4S flavoprotein located in the inner mitochondrial membrane and catalyses ubiquinone (UQ) reduction. It forms a single structural domain with three functional regions (that b ...Electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO) is a a 4Fe4S flavoprotein located in the inner mitochondrial membrane and catalyses ubiquinone (UQ) reduction. It forms a single structural domain with three functional regions (that bind FAD, the 4Fe4S cluster, and UQ) which are closely packed and share structural elements [1]. This domain includes the residues involved in UQ binding [1]. This domain is also found in FixC proteins from bacteria, which share similarities with ETF-QO [2].
Domain
A, B
PF05187Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S (ETF_QO)Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S- Family
A, B
PF13450NAD(P)-binding Rossmann-like domain (NAD_binding_8)NAD(P)-binding Rossmann-like domain- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Electron transfer flavoprotein-ubiquinone oxidoreductase