Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
G [auth A]DNA_pol_lambd_fe2ihmA4 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: SAM domain-likeF: DNA_pol_lambd_fECOD (1.6)
G [auth A]HHH_8e2ihmA2 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: SAM domain-likeF: HHH_8ECOD (1.6)
G [auth A]DNA_pol_B_palme2ihmA3 A: a+b three layersX: Nucleotidyltransferase-likeH: Nucleotidyltransferase (From Topology)T: NucleotidyltransferaseF: DNA_pol_B_palmECOD (1.6)
H [auth B]DNA_pol_lambd_fe2ihmB2 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: SAM domain-likeF: DNA_pol_lambd_fECOD (1.6)
H [auth B]HHH_8e2ihmB3 A: alpha arraysX: HhH/H2THH: SAM/DNA-glycosylaseT: SAM domain-likeF: HHH_8ECOD (1.6)
H [auth B]DNA_pol_B_palme2ihmB1 A: a+b three layersX: Nucleotidyltransferase-likeH: Nucleotidyltransferase (From Topology)T: NucleotidyltransferaseF: DNA_pol_B_palmECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
G [auth A],
H [auth B]
PF14716Helix-hairpin-helix domain (HHH_8)Helix-hairpin-helix domain- Domain
G [auth A],
H [auth B]
PF14791DNA polymerase beta thumb (DNA_pol_B_thumb)DNA polymerase beta thumb- Family
G [auth A],
H [auth B]
PF14792DNA polymerase beta palm (DNA_pol_B_palm)DNA polymerase beta palmThe catalytic region of DNA polymerase beta is split into three domains. An N-terminal fingers domain, a central palm domain and a C-terminal thumb domain. This entry represents the palm domain [1].Domain
G [auth A],
H [auth B]
PF10391Fingers domain of DNA polymerase lambda (DNA_pol_lambd_f)Fingers domain of DNA polymerase lambdaDNA polymerases catalyse the addition of dNMPs onto the 3-prime ends of DNA chains. There is a general polymerase fold consisting of three subdomains that have been likened to the fingers, palm, and thumb of a right hand. DNA_pol_lambd_f is the centr ...DNA polymerases catalyse the addition of dNMPs onto the 3-prime ends of DNA chains. There is a general polymerase fold consisting of three subdomains that have been likened to the fingers, palm, and thumb of a right hand. DNA_pol_lambd_f is the central three-helical region of DNA polymerase lambda referred to as the F and G helices of the fingers domain. Contacts with DNA involve this conserved helix-hairpin-helix motif in the fingers region which interacts with the primer strand. This motif is common to several DNA binding proteins and confers a sequence-independent interaction with the DNA backbone [1].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth T],
D [auth U]
5'-D(*CP*GP*GP*CP*AP*AP*TP*AP*CP*TP*G)-3'---
B [auth P],
E [auth Q]
5'-D(*CP*AP*GP*TP*AP*T)-3'---
C [auth D],
F [auth E]
5'-D(P*GP*CP*CP*G)-3'---
G [auth A],
H [auth B]
DNA polymerase mu