2II3

Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), Oxidized Coenzyme A-bound form


Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad2ii3a_ Alpha and beta proteins (a/b) CoA-dependent acyltransferases CoA-dependent acyltransferases automated matches automated matches cattle (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Bd2ii3b_ Alpha and beta proteins (a/b) CoA-dependent acyltransferases CoA-dependent acyltransferases automated matches automated matches cattle (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Cd2ii3c_ Alpha and beta proteins (a/b) CoA-dependent acyltransferases CoA-dependent acyltransferases automated matches automated matches cattle (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Dd2ii3d_ Alpha and beta proteins (a/b) CoA-dependent acyltransferases CoA-dependent acyltransferases automated matches automated matches cattle (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Ed2ii3e_ Alpha and beta proteins (a/b) CoA-dependent acyltransferases CoA-dependent acyltransferases automated matches automated matches cattle (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Fd2ii3f_ Alpha and beta proteins (a/b) CoA-dependent acyltransferases CoA-dependent acyltransferases automated matches automated matches cattle (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Gd2ii3g_ Alpha and beta proteins (a/b) CoA-dependent acyltransferases CoA-dependent acyltransferases automated matches automated matches cattle (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Hd2ii3h_ Alpha and beta proteins (a/b) CoA-dependent acyltransferases CoA-dependent acyltransferases automated matches automated matches cattle (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyCoA-dependent acyltransferases 8076201 3000272 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyCoA-dependent acyltransferases 8076201 3000272 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyCoA-dependent acyltransferases 8076201 3000272 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyCoA-dependent acyltransferases 8076201 3000272 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyCoA-dependent acyltransferases 8076201 3000272 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyCoA-dependent acyltransferases 8076201 3000272 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyCoA-dependent acyltransferases 8076201 3000272 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyCoA-dependent acyltransferases 8076201 3000272 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A2-oxoacid_dhe2ii3A1 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: 2-oxoacid_dhECOD (1.6)
B2-oxoacid_dhe2ii3B1 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: 2-oxoacid_dhECOD (1.6)
C2-oxoacid_dhe2ii3C1 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: 2-oxoacid_dhECOD (1.6)
D2-oxoacid_dhe2ii3D1 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: 2-oxoacid_dhECOD (1.6)
E2-oxoacid_dhe2ii3E1 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: 2-oxoacid_dhECOD (1.6)
F2-oxoacid_dhe2ii3F1 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: 2-oxoacid_dhECOD (1.6)
G2-oxoacid_dhe2ii3G1 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: 2-oxoacid_dhECOD (1.6)
H2-oxoacid_dhe2ii3H1 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: 2-oxoacid_dhECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, B, C, D, E
IPR0010782-oxoacid dehydrogenase acyltransferase, catalytic domainDomain
A, B, C, D, E
IPR023213Chloramphenicol acetyltransferase-like domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR036625E3-binding domain superfamilyHomologous Superfamily
A, B, C, D, E
IPR0507432-oxoacid dehydrogenase family, E2 componentFamily
A, B, C, D, E
IPR004167Peripheral subunit-binding domainDomain
A, B, C, D, E
IPR011053Single hybrid motifHomologous Superfamily
A, B, C, D, E
IPR0030162-oxo acid dehydrogenase, lipoyl-binding siteBinding Site
A, B, C, D, E
IPR000089Biotin/lipoyl attachmentDomain