Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth B]TetR_Ne3br2B1 A: alpha arraysX: HTHH: HTHT: tri-helicalF: TetR_NECOD (1.6)
A [auth B]TetR_C_5e3br2B2 A: alpha bundlesX: Tetracyclin repressor-like, C-terminal domain (From Topology)H: Tetracyclin repressor-like, C-terminal domain (From Topology)T: Tetracyclin repressor-like, C-terminal domainF: TetR_C_5ECOD (1.6)
B [auth D]TetR_Ne3br2D1 A: alpha arraysX: HTHH: HTHT: tri-helicalF: TetR_NECOD (1.6)
B [auth D]TetR_C_5e3br2D2 A: alpha bundlesX: Tetracyclin repressor-like, C-terminal domain (From Topology)H: Tetracyclin repressor-like, C-terminal domain (From Topology)T: Tetracyclin repressor-like, C-terminal domainF: TetR_C_5ECOD (1.6)
C [auth A]TetR_Ne3br2A1 A: alpha arraysX: HTHH: HTHT: tri-helicalF: TetR_NECOD (1.6)
C [auth A]TetR_C_5e3br2A2 A: alpha bundlesX: Tetracyclin repressor-like, C-terminal domain (From Topology)H: Tetracyclin repressor-like, C-terminal domain (From Topology)T: Tetracyclin repressor-like, C-terminal domainF: TetR_C_5ECOD (1.6)
D [auth E]TetR_Ne3br2E1 A: alpha arraysX: HTHH: HTHT: tri-helicalF: TetR_NECOD (1.6)
D [auth E]TetR_C_5e3br2E2 A: alpha bundlesX: Tetracyclin repressor-like, C-terminal domain (From Topology)H: Tetracyclin repressor-like, C-terminal domain (From Topology)T: Tetracyclin repressor-like, C-terminal domainF: TetR_C_5ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth B],
B [auth D],
C [auth A],
D [auth E]
PF00440Bacterial regulatory proteins, tetR family (TetR_N)Bacterial regulatory proteins, tetR family- Domain
A [auth B],
B [auth D],
C [auth A],
D [auth E]
PF08360QacR-like protein, C-terminal region (TetR_C_5)QacR-like protein, C-terminal regionThis family features the C-terminal region of a number of proteins that bear similarity to the QacR protein (Swiss:P23217), a transcriptional regulator of the TetR family. QacR is able to bind various environmental agents, which include a number of c ...This family features the C-terminal region of a number of proteins that bear similarity to the QacR protein (Swiss:P23217), a transcriptional regulator of the TetR family. QacR is able to bind various environmental agents, which include a number of cationic lipophilic compounds, and thus regulate the transcription of QacA (Swiss:P23215), a multidrug efflux pump [1]. The C-terminal region contains the multifaceted, expansive drug-binding pocket, which is composed of several separate, but linked, binding sites [2].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth B],
B [auth D],
C [auth A],
D [auth E]
HTH-type transcriptional regulator qacR -