Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyGSR C-terminal domain-like 8056200 3000028 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyThioredoxin reductase-like 8056199 3000050 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APyr_redox_dime3eanA6 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
APyr_redox_2_1e3eanA5 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
APyr_redox_2e3eanA4 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
BPyr_redox_dime3eanB6 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
BPyr_redox_2_1e3eanB5 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
BPyr_redox_2e3eanB4 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
CPyr_redox_dime3eanC6 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
CPyr_redox_2_1e3eanC5 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
CPyr_redox_2e3eanC4 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
DPyr_redox_dime3eanD6 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
DPyr_redox_2_1e3eanD5 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
DPyr_redox_2e3eanD4 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
EPyr_redox_dime3eanE6 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
EPyr_redox_2_1e3eanE5 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
EPyr_redox_2e3eanE4 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)
FPyr_redox_dime3eanF6 A: a+b two layersX: FAD-linked reductases, C-terminal domain-likeH: FAD/NAD-linked reduatases, dimerisation (C-terminal) domain (From Topology)T: FAD/NAD-linked reduatases, dimerisation (C-terminal) domainF: Pyr_redox_dimECOD (1.6)
FPyr_redox_2_1e3eanF5 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2_1ECOD (1.6)
FPyr_redox_2e3eanF4 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: FAD/NAD(P)-binding domainF: Pyr_redox_2ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00070Pyridine nucleotide-disulphide oxidoreductase (Pyr_redox)Pyridine nucleotide-disulphide oxidoreductaseThis family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.Domain
A, B, C, D, E
PF00890FAD binding domain (FAD_binding_2)FAD binding domain- Family
A, B, C, D, E
PF02852Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain (Pyr_redox_dim)Pyridine nucleotide-disulphide oxidoreductase, dimerisation domainThis family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
Thioredoxin reductase 1