Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyThymidylate synthase/dCMP hydroxymethylase 8036156 3000544 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyThymidylate synthase/dCMP hydroxymethylase 8036156 3000544 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyThymidylate synthase/dCMP hydroxymethylase 8036156 3000544 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyThymidylate synthase/dCMP hydroxymethylase 8036156 3000544 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyThymidylate synthase/dCMP hydroxymethylase 8036156 3000544 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AThymidylat_synte3h9kA1 A: a+b two layersX: Thymidylate synthase/dCMP hydroxymethylase (From Topology)H: Thymidylate synthase/dCMP hydroxymethylase (From Topology)T: Thymidylate synthase/dCMP hydroxymethylaseF: Thymidylat_syntECOD (1.6)
BThymidylat_synte3h9kB1 A: a+b two layersX: Thymidylate synthase/dCMP hydroxymethylase (From Topology)H: Thymidylate synthase/dCMP hydroxymethylase (From Topology)T: Thymidylate synthase/dCMP hydroxymethylaseF: Thymidylat_syntECOD (1.6)
DThymidylat_synte3h9kD1 A: a+b two layersX: Thymidylate synthase/dCMP hydroxymethylase (From Topology)H: Thymidylate synthase/dCMP hydroxymethylase (From Topology)T: Thymidylate synthase/dCMP hydroxymethylaseF: Thymidylat_syntECOD (1.6)
CThymidylat_synte3h9kC1 A: a+b two layersX: Thymidylate synthase/dCMP hydroxymethylase (From Topology)H: Thymidylate synthase/dCMP hydroxymethylase (From Topology)T: Thymidylate synthase/dCMP hydroxymethylaseF: Thymidylat_syntECOD (1.6)
EThymidylat_synte3h9kE1 A: a+b two layersX: Thymidylate synthase/dCMP hydroxymethylase (From Topology)H: Thymidylate synthase/dCMP hydroxymethylase (From Topology)T: Thymidylate synthase/dCMP hydroxymethylaseF: Thymidylat_syntECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase Chain ACATH (4.3.0)
B3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase Chain ACATH (4.3.0)
D3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase Chain ACATH (4.3.0)
C3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase Chain ACATH (4.3.0)
E3.30.572.10 Alpha Beta 2-Layer Sandwich Thymidylate Synthase Chain ACATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D, E
PF00303Thymidylate synthase (Thymidylat_synt)Thymidylate synthaseThis is a family of proteins that are flavin-dependent thymidylate synthases.Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D, E
Thymidylate synthase

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
A, B, C, D, E
PharosP04818