Annotations: 3QYF

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Cas_APE2256-like	8045334	4004418	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	PIN domain-like	8090252	3001041	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Winged helix DNA-binding domain	8090253	3000034	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	PIN domain-like	8090252	3001041	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Winged helix DNA-binding domain	8090253	3000034	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	COG4006	e3qyfA2	A: alpha arrays	X: HTH	H: HTH	T: winged	F: COG4006	ECOD (1.6)
A	Cas_APE2256	e3qyfA1	A: a/b three-layered sandwiches	X: CARF (CRISPR-associated Rossmann fold) domains (From Topology)	H: CARF (CRISPR-associated Rossmann fold) domains (From Topology)	T: CARF (CRISPR-associated Rossmann fold) domains	F: Cas_APE2256	ECOD (1.6)
B	COG4006	e3qyfB1	A: alpha arrays	X: HTH	H: HTH	T: winged	F: COG4006	ECOD (1.6)
B	Cas_APE2256	e3qyfB2	A: a/b three-layered sandwiches	X: CARF (CRISPR-associated Rossmann fold) domains (From Topology)	H: CARF (CRISPR-associated Rossmann fold) domains (From Topology)	T: CARF (CRISPR-associated Rossmann fold) domains	F: Cas_APE2256	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.40.50.10770	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Hypothetical protein VC1899 like domain (Restriction endonuclease-like)	CATH (4.3.0)
A	1.10.196.30	Mainly Alpha	Orthogonal Bundle	Regulator of G-protein Signalling 4	domain 1	CATH (4.3.0)
A	1.10.10.1690	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Uncharacterised CRISPR-associated protein family, UPF0236	CATH (4.3.0)
B	3.40.50.10770	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Hypothetical protein VC1899 like domain (Restriction endonuclease-like)	CATH (4.3.0)
B	1.10.196.30	Mainly Alpha	Orthogonal Bundle	Regulator of G-protein Signalling 4	domain 1	CATH (4.3.0)
B	1.10.10.1690	Mainly Alpha	Orthogonal Bundle	Arc Repressor Mutant, subunit A	Uncharacterised CRISPR-associated protein family, UPF0236	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF09651	CRISPR-associated protein (Cas_APE2256) (Cas_APE2256)	CRISPR-associated protein (Cas_APE2256)	-	Family
A, B	PF22165	SSO1393-like, winged-helix domain (SSO1393-like_WHD)	SSO1393-like, winged-helix domain	This entry represents a WH-like domain present in SSO1393-like proteins. SSO1393 is an archaeal protein from Sulfolobus solfataricus (PDB:3qyf). This protein has been described as a component of the CRISPR system [1]. CRISPR (clustered regularly inte ...	This entry represents a WH-like domain present in SSO1393-like proteins. SSO1393 is an archaeal protein from Sulfolobus solfataricus (PDB:3qyf). This protein has been described as a component of the CRISPR system [1]. CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids) [1,2].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	CRISPR-ASSOCIATED PROTEIN	lyase activity catalytic activity	biological process involved in interspecies interaction between organisms response to stimulus response to other organism defense response defense response to symbiont response to external stimulus response to biotic stimulus defense response to virus defense response to other organism response to stress response to external biotic stimulus response to virus	intracellular anatomical structure cytoplasm cellular anatomical entity

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR016620	CRISPR system ring nuclease SSO1393	Family
A, B	IPR054041	CRISPR system ring nuclease SSO1393-like, winged-helix domain	Domain
A, B	IPR013442	CRISPR system ring nuclease SSO1393-like	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.