Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
CSCOP2 FamilyPicornaviridae-like VP (VP1, VP2, VP3 and VP4) 8068029 4003466 SCOP2 (2022-06-29)
CSCOP2 SuperfamilyPositive stranded ssRNA viruses-like 8068030 3000918 SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ARhv_5e3vbfA1 A: beta sandwichesX: jelly-rollH: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)T: Nucleoplasmin-like/VP (viral coat and capsid proteins)F: Rhv_5ECOD (1.6)
BRhv_1e3vbfB1 A: beta sandwichesX: jelly-rollH: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)T: Nucleoplasmin-like/VP (viral coat and capsid proteins)F: Rhv_1ECOD (1.6)
CRhv_3e3vbfC1 A: beta sandwichesX: jelly-rollH: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)T: Nucleoplasmin-like/VP (viral coat and capsid proteins)F: Rhv_3ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.60.120.20 Mainly Beta Sandwich Jelly Rolls CATH (4.3.0)
B2.60.120.20 Mainly Beta Sandwich Jelly Rolls CATH (4.3.0)
C2.60.120.20 Mainly Beta Sandwich Jelly Rolls CATH (4.3.0)
D4.10.80.370 Few Secondary Structures Irregular Rhinovirus 14, subunit 4 CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF22663Picornavirus coat protein (Rhv_5)Picornavirus coat proteinThis domain is found in capsid proteins from picornavirus, such as enterovirus, rhinovirus and foot-and-mouth disease virus [1-5].Domain
PF00073picornavirus capsid protein (Rhv)picornavirus capsid proteinCAUTION: This alignment is very weak. It can not be generated by clustalw. If a representative set is used for a seed, many so-called members are not recognised. The family should probably be split up into sub-families. Capsid proteins of picornavi ...CAUTION: This alignment is very weak. It can not be generated by clustalw. If a representative set is used for a seed, many so-called members are not recognised. The family should probably be split up into sub-families. Capsid proteins of picornaviruses. Picornaviruses are non-enveloped plus-strand ssRNA animal viruses with icosahedral capsids. They include rhinovirus (common cold) and poliovirus. Common structure is an 8-stranded beta sandwich. Variations (one or two extra strands) occur.
Domain
PF00073picornavirus capsid protein (Rhv)picornavirus capsid proteinCAUTION: This alignment is very weak. It can not be generated by clustalw. If a representative set is used for a seed, many so-called members are not recognised. The family should probably be split up into sub-families. Capsid proteins of picornavi ...CAUTION: This alignment is very weak. It can not be generated by clustalw. If a representative set is used for a seed, many so-called members are not recognised. The family should probably be split up into sub-families. Capsid proteins of picornaviruses. Picornaviruses are non-enveloped plus-strand ssRNA animal viruses with icosahedral capsids. They include rhinovirus (common cold) and poliovirus. Common structure is an 8-stranded beta sandwich. Variations (one or two extra strands) occur.
Domain
PF02226Picornavirus coat protein (VP4) (Pico_P1A)Picornavirus coat protein (VP4)- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Genome Polyprotein, capsid protein VP1
Genome Polyprotein, capsid protein VP2
Genome Polyprotein, capsid protein VP3
Genome Polyprotein, capsid protein VP4

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR001205RNA-directed RNA polymerase, C-terminal domainDomain
IPR002527Picornavirus 2B proteinDomain
IPR043128Reverse transcriptase/Diguanylate cyclase domainHomologous Superfamily
IPR003593AAA+ ATPase domainDomain
IPR003138Picornavirus coat protein VP4Family
IPR000199Peptidase C3A/C3B, picornaviralDomain
IPR001676Picornavirus capsidDomain
IPR014759Helicase, superfamily 3, single-stranded RNA virusDomain
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
IPR000081Peptidase C3, picornavirus core protein 2ADomain
IPR029053Viral coat protein subunitHomologous Superfamily
IPR009003Peptidase S1, PA clanHomologous Superfamily
IPR043502DNA/RNA polymerase superfamilyHomologous Superfamily
IPR044067Picornavirales 3C/3C-like protease domainDomain
IPR033703Picornavirus/Calicivirus coat proteinDomain
IPR014838Poliovirus 3A protein-likeDomain
IPR036203Poliovirus core protein 3a, soluble domainHomologous Superfamily
IPR043504Peptidase S1, PA clan, chymotrypsin-like foldHomologous Superfamily
IPR007094RNA-directed RNA polymerase, catalytic domainDomain
IPR000605Helicase, superfamily 3, single-stranded DNA/RNA virusDomain
IPR001205RNA-directed RNA polymerase, C-terminal domainDomain
IPR002527Picornavirus 2B proteinDomain
IPR043128Reverse transcriptase/Diguanylate cyclase domainHomologous Superfamily
IPR003593AAA+ ATPase domainDomain
IPR003138Picornavirus coat protein VP4Family
IPR000199Peptidase C3A/C3B, picornaviralDomain
IPR001676Picornavirus capsidDomain
IPR014759Helicase, superfamily 3, single-stranded RNA virusDomain
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
IPR000081Peptidase C3, picornavirus core protein 2ADomain
IPR029053Viral coat protein subunitHomologous Superfamily
IPR009003Peptidase S1, PA clanHomologous Superfamily
IPR043502DNA/RNA polymerase superfamilyHomologous Superfamily
IPR044067Picornavirales 3C/3C-like protease domainDomain
IPR033703Picornavirus/Calicivirus coat proteinDomain
IPR014838Poliovirus 3A protein-likeDomain
IPR036203Poliovirus core protein 3a, soluble domainHomologous Superfamily
IPR043504Peptidase S1, PA clan, chymotrypsin-like foldHomologous Superfamily
IPR007094RNA-directed RNA polymerase, catalytic domainDomain
IPR000605Helicase, superfamily 3, single-stranded DNA/RNA virusDomain
IPR001205RNA-directed RNA polymerase, C-terminal domainDomain
IPR002527Picornavirus 2B proteinDomain
IPR043128Reverse transcriptase/Diguanylate cyclase domainHomologous Superfamily
IPR003593AAA+ ATPase domainDomain
IPR003138Picornavirus coat protein VP4Family
IPR000199Peptidase C3A/C3B, picornaviralDomain
IPR001676Picornavirus capsidDomain
IPR014759Helicase, superfamily 3, single-stranded RNA virusDomain
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
IPR000081Peptidase C3, picornavirus core protein 2ADomain
IPR029053Viral coat protein subunitHomologous Superfamily
IPR009003Peptidase S1, PA clanHomologous Superfamily
IPR043502DNA/RNA polymerase superfamilyHomologous Superfamily
IPR044067Picornavirales 3C/3C-like protease domainDomain
IPR033703Picornavirus/Calicivirus coat proteinDomain
IPR014838Poliovirus 3A protein-likeDomain
IPR036203Poliovirus core protein 3a, soluble domainHomologous Superfamily
IPR043504Peptidase S1, PA clan, chymotrypsin-like foldHomologous Superfamily
IPR007094RNA-directed RNA polymerase, catalytic domainDomain
IPR000605Helicase, superfamily 3, single-stranded DNA/RNA virusDomain
IPR001205RNA-directed RNA polymerase, C-terminal domainDomain
IPR002527Picornavirus 2B proteinDomain
IPR043128Reverse transcriptase/Diguanylate cyclase domainHomologous Superfamily
IPR003593AAA+ ATPase domainDomain
IPR003138Picornavirus coat protein VP4Family
IPR000199Peptidase C3A/C3B, picornaviralDomain
IPR001676Picornavirus capsidDomain
IPR014759Helicase, superfamily 3, single-stranded RNA virusDomain
IPR027417P-loop containing nucleoside triphosphate hydrolaseHomologous Superfamily
IPR000081Peptidase C3, picornavirus core protein 2ADomain
IPR029053Viral coat protein subunitHomologous Superfamily
IPR009003Peptidase S1, PA clanHomologous Superfamily
IPR043502DNA/RNA polymerase superfamilyHomologous Superfamily
IPR044067Picornavirales 3C/3C-like protease domainDomain
IPR033703Picornavirus/Calicivirus coat proteinDomain
IPR014838Poliovirus 3A protein-likeDomain
IPR036203Poliovirus core protein 3a, soluble domainHomologous Superfamily
IPR043504Peptidase S1, PA clan, chymotrypsin-like foldHomologous Superfamily
IPR007094RNA-directed RNA polymerase, catalytic domainDomain
IPR000605Helicase, superfamily 3, single-stranded DNA/RNA virusDomain