Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyNucleotide-diphospho-sugar transferases 8099200 3000077 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ATcdA_TcdB_pore_2nde4r04A5 A: beta duplicates or obligate multimersX: Toxin A (TcdA) delivery domain (From Topology)H: Toxin A (TcdA) delivery domain (From Topology)T: Toxin A (TcdA) delivery domainF: TcdA_TcdB_pore_2ndECOD (1.6)
ATcdA_TcdB_pore_1ste4r04A4 A: alpha arraysX: Toxin A (TcdA) helical domain (From Topology)H: Toxin A (TcdA) helical domain (From Topology)T: Toxin A (TcdA) helical domainF: TcdA_TcdB_pore_1stECOD (1.6)
AMLDe4r04A1 A: alpha bundlesX: Bromodomain-likeH: PMT helical bundle domain-likeT: PMT helical bundle domain-likeF: MLDECOD (1.6)
ATcdA_TcdBe4r04A2 A: a/b three-layered sandwichesX: Nucleotide-diphospho-sugar transferases (From Topology)H: Nucleotide-diphospho-sugar transferases (From Topology)T: Nucleotide-diphospho-sugar transferasesF: TcdA_TcdBECOD (1.6)
APeptidase_C80e4r04A3 A: a/b three-layered sandwichesX: Caspase-like (From Topology)H: Caspase-like (From Topology)T: Caspase-likeF: Peptidase_C80ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF12919TcdA/TcdB catalytic glycosyltransferase domain (TcdA_TcdB)TcdA/TcdB catalytic glycosyltransferase domainThis domain represents the N-terminal glycosyltransferase from a set of toxins found in some bacteria. This domain in TcdB glycosylates the host RhoA protein.Domain
PF12918TcdB toxin N-terminal helical domain (TcdB_N)TcdB toxin N-terminal helical domainThis is a short helical bundle domain found associated with the catalytic domain of the TcdB toxin from C. difficile [1]. The function of this domain is unknown, but it may be involved in substrate recognition.Domain
PF11713Peptidase C80 family (Peptidase_C80)Peptidase C80 familyThis family belongs to cysteine peptidase family C80.Domain
PF12920TcdA/TcdB pore forming domain (TcdA_TcdB_pore)TcdA/TcdB pore forming domain- Family