Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AHisKA_2e4r39A2 A: alpha duplicates or obligate multimersX: ROP-likeH: Homodimeric domain of signal transducing histidine kinase (From Topology)T: Homodimeric domain of signal transducing histidine kinaseF: HisKA_2ECOD (1.6)
AHATPase_c_2e4r39A1 A: a+b two layersX: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-likeH: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinaseF: HATPase_c_2ECOD (1.6)
BHisKA_2e4r39B2 A: alpha duplicates or obligate multimersX: ROP-likeH: Homodimeric domain of signal transducing histidine kinase (From Topology)T: Homodimeric domain of signal transducing histidine kinaseF: HisKA_2ECOD (1.6)
BHATPase_c_2e4r39B1 A: a+b two layersX: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-likeH: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinaseF: HATPase_c_2ECOD (1.6)
DHisKA_2e4r39D2 A: alpha duplicates or obligate multimersX: ROP-likeH: Homodimeric domain of signal transducing histidine kinase (From Topology)T: Homodimeric domain of signal transducing histidine kinaseF: HisKA_2ECOD (1.6)
DHATPase_c_2e4r39D1 A: a+b two layersX: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-likeH: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinaseF: HATPase_c_2ECOD (1.6)
CHisKA_2e4r39C2 A: alpha duplicates or obligate multimersX: ROP-likeH: Homodimeric domain of signal transducing histidine kinase (From Topology)T: Homodimeric domain of signal transducing histidine kinaseF: HisKA_2ECOD (1.6)
CHATPase_c_2e4r39C1 A: a+b two layersX: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-likeH: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology)T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinaseF: HATPase_c_2ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF02518Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)Histidine kinase-, DNA gyrase B-, and HSP90-like ATPaseThis family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90.Domain
A, B, C, D
PF07568Histidine kinase (HisKA_2)Histidine kinaseThis is the dimerisation and phosphoacceptor domain of a sub-family of histidine kinases [1]. It shares sequence similarity with Pfam:PF00512 and Pfam:PF07536 [2]. It is usually found adjacent to a C-terminal ATPase domain (Pfam:PF02518). This domain ...This is the dimerisation and phosphoacceptor domain of a sub-family of histidine kinases [1]. It shares sequence similarity with Pfam:PF00512 and Pfam:PF07536 [2]. It is usually found adjacent to a C-terminal ATPase domain (Pfam:PF02518). This domain is found in a wide range of Bacteria and also several Archaea.
Domain