Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8054579 3000071 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyMHC antigen-recognition domain 8033653 3000521 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8003766 3000071 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyImmunoglobulin (Ig) domain-like 8059449 3000071 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AC1-set_2e5menA1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
AMHC_Ie5menA2 A: a+b two layersX: MHC antigen-recognition domain (From Topology)H: MHC antigen-recognition domain (From Topology)T: MHC antigen-recognition domainF: MHC_IECOD (1.6)
BC1-set_2e5menB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-set_2ECOD (1.6)
DDUF1968e5menD2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: DUF1968ECOD (1.6)
DV-set_3e5menD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)
EC1-sete5menE1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: C1-setECOD (1.6)
EV-set_3e5menE2 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Immunoglobulin/Fibronectin type III/E set domains/PapD-likeF: V-set_3ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00129Class I Histocompatibility antigen, domains alpha 1 and 2 (MHC_I)Class I Histocompatibility antigen, domains alpha 1 and 2- Domain
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain
PF07686Immunoglobulin V-set domain (V-set)Immunoglobulin V-set domainThis domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.Domain
PF09291Domain of unknown function (DUF1968) (DUF1968)Domain of unknown function (DUF1968)Members of this family are found in mammalian T-cell antigen receptor, and adopt an immunoglobulin-like beta-sandwich fold, with seven strands in two beta-sheets in a Greek-key topology. Their exact function has not, as yet, been determined.Domain
PF07686Immunoglobulin V-set domain (V-set)Immunoglobulin V-set domainThis domain is found in antibodies as well as neural protein P0 and CTL4 amongst others.Domain
PF07654Immunoglobulin C1-set domain (C1-set)Immunoglobulin C1-set domain- Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
HLA class I histocompatibility antigen, A-2 alpha chain
Beta-2-microglobulin
ILE-LEU-ALA-LYS-PHE-LEU-HIS-TRP-LEU
Protein TRAV22,Human nkt tcr alpha chain-
Protein TRBV6-5,Human nkt tcr beta chain

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
IPR010579MHC class I, alpha chain, C-terminalDomain
IPR011162MHC classes I/II-like antigen recognition proteinHomologous Superfamily
IPR001039MHC class I alpha chain, alpha1 alpha2 domainsDomain
IPR003006Immunoglobulin/major histocompatibility complex, conserved siteConserved Site
IPR013783Immunoglobulin-like foldHomologous Superfamily
IPR007110Immunoglobulin-like domainDomain
IPR050208Antigen-presenting and immune regulatory MHC class I-relatedFamily
IPR003597Immunoglobulin C1-setDomain
IPR011161MHC class I-like antigen recognition-likeDomain
IPR037055MHC class I-like antigen recognition-like superfamilyHomologous Superfamily
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
IPR003006Immunoglobulin/major histocompatibility complex, conserved siteConserved Site
IPR013783Immunoglobulin-like foldHomologous Superfamily
IPR007110Immunoglobulin-like domainDomain
IPR050160Major Histocompatibility Complex/ImmunoglobulinFamily
IPR003597Immunoglobulin C1-setDomain
IPR015707Beta-2-MicroglobulinFamily
IPR021891Telomerase ribonucleoprotein complex - RNA-binding domainDomain
IPR049139Telomerase reverse transcriptase, C-terminal extensionDomain
IPR043502DNA/RNA polymerase superfamilyHomologous Superfamily
IPR000477Reverse transcriptase domainDomain
IPR003545Telomerase reverse transcriptaseFamily
IPR051896T cell receptor alpha variable regionFamily
IPR013783Immunoglobulin-like foldHomologous Superfamily
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
IPR013106Immunoglobulin V-set domainDomain
IPR007110Immunoglobulin-like domainDomain
IPR052051T cell receptor complex componentFamily
IPR013783Immunoglobulin-like foldHomologous Superfamily
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
IPR013106Immunoglobulin V-set domainDomain
IPR003599Immunoglobulin domain subtypeDomain
IPR007110Immunoglobulin-like domainDomain
IPR015370T-cell receptor alpha chain, constant domainDomain
IPR013783Immunoglobulin-like foldHomologous Superfamily
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
IPR013106Immunoglobulin V-set domainDomain
IPR007110Immunoglobulin-like domainDomain
IPR050413T cell receptor beta variableFamily
IPR003597Immunoglobulin C1-setDomain
IPR013783Immunoglobulin-like foldHomologous Superfamily
IPR036179Immunoglobulin-like domain superfamilyHomologous Superfamily
IPR013106Immunoglobulin V-set domainDomain
IPR003599Immunoglobulin domain subtypeDomain
IPR007110Immunoglobulin-like domainDomain
IPR050413T cell receptor beta variableFamily

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
PharosP04439
PharosP61769
PharosO14746
PharosA0A0B4J277
PharosA0A0K0K1A5