Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
A [auth D]SCOP2B SuperfamilySMAD/FHA domain-like 8088232 3000137 SCOP2B (2022-06-29)
B [auth A]SCOP2B SuperfamilySMAD/FHA domain-like 8088232 3000137 SCOP2B (2022-06-29)
C [auth B]SCOP2 FamilyFHA domain 8088231 4002605 SCOP2 (2022-06-29)
C [auth B]SCOP2 SuperfamilySMAD/FHA domain-like 8088232 3000137 SCOP2 (2022-06-29)
D [auth C]SCOP2B SuperfamilySMAD/FHA domain-like 8088232 3000137 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
A [auth D]FHA_1e5w7xD1 A: beta sandwichesX: SMAD/FHA domain (From Topology)H: SMAD/FHA domain (From Topology)T: SMAD/FHA domainF: FHA_1ECOD (1.6)
B [auth A]FHA_1e5w7xA1 A: beta sandwichesX: SMAD/FHA domain (From Topology)H: SMAD/FHA domain (From Topology)T: SMAD/FHA domainF: FHA_1ECOD (1.6)
C [auth B]FHA_1e5w7xB1 A: beta sandwichesX: SMAD/FHA domain (From Topology)H: SMAD/FHA domain (From Topology)T: SMAD/FHA domainF: FHA_1ECOD (1.6)
D [auth C]FHA_1e5w7xC1 A: beta sandwichesX: SMAD/FHA domain (From Topology)H: SMAD/FHA domain (From Topology)T: SMAD/FHA domainF: FHA_1ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A [auth D]2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 CATH (4.3.0)
B [auth A]2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 CATH (4.3.0)
C [auth B]2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 CATH (4.3.0)
D [auth C]2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A [auth D],
B [auth A],
C [auth B],
D [auth C]
PF17913FHA domain (FHA_2)FHA domainThis entry represents a divergent FHA domain which in PNK binds to phosphorylated segment of XRCC1 [1].Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A [auth D],
B [auth A],
C [auth B],
D [auth C]
Aprataxin and PNK-like factor
E [auth H],
F [auth E],
G [auth F],
H [auth G]
DNA repair protein XRCC1

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
E [auth H],
F [auth E],
G [auth F],
H [auth G]
SEP Parent Component: SER

RESIDAA0037

PSI-MOD :  O-phospho-L-serine MOD:00046
E [auth H],
F [auth E],
G [auth F],
H [auth G]
TPO Parent Component: THR

RESIDAA0037 , AA0038

PSI-MOD :  O-phospho-L-serine MOD:00046 , O-phospho-L-threonine MOD:00047