Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad6bc7a_ Alpha and beta proteins (a/b) TTHA0583/YokD-like TTHA0583/YokD-like automated matches automated matches (Enterobacter cloacae ) [TaxId: 550 ], SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
AAntibiotic_NATe6bc7A1 A: a/b three-layered sandwichesX: Hypothetical protein TT1679 (From Topology)H: Hypothetical protein TT1679 (From Topology)T: Hypothetical protein TT1679F: Antibiotic_NATECOD (1.6)

AMR Gene: CARD Annotation CARD Database Homepage

ChainsAccessionShort NameDescriptionProvenance Source (Version)
ARO:3002540AAC(3)-VIaAAC(3)-VIa is a plasmid-encoded aminoglycoside acetyltransferase in E. cloacae, S. enterica and E. coli.CARD (3.3.0)

AMR Gene Family: CARD Annotation CARD Database Homepage

ChainsAccessionGene FamilyDrug Class Resistance MachanismProvenance Source (Version)
ARO:3000322AAC(3)aminoglycoside antibioticantibiotic inactivationCARD (3.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF02522Aminoglycoside 3-N-acetyltransferase (Antibiotic_NAT)Aminoglycoside 3-N-acetyltransferaseThis family consists of bacterial aminoglycoside 3-N-acetyltransferases EC:2.3.1.81, these catalyse the reaction: Acetyl-Co + a 2-deoxystreptamine antibiotic <=> CoA + N3'-acetyl-2-deoxystreptamine antibiotic. The enzyme can use ...This family consists of bacterial aminoglycoside 3-N-acetyltransferases EC:2.3.1.81, these catalyse the reaction: Acetyl-Co + a 2-deoxystreptamine antibiotic <=> CoA + N3'-acetyl-2-deoxystreptamine antibiotic. The enzyme can use a range of antibiotics with 2-deoxystreptamine rings as acceptor for its acetyltransferase activity, this inactivates and confers resistance to gentamicin, kanamycin, tobramycin, neomycin and apramycin amongst others.
Domain

InterPro: Protein Family Classification InterPro Database Homepage