Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
BSCOP2B SuperfamilyVirus ectodomain 8039635 3001628 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
BEbola-like_HR1-HR2e6hs4B1 A: a+b duplicates or obligate multimersX: Envelope glycoprotein GP2-related (From Topology)H: Envelope glycoprotein GP2-related (From Topology)T: Envelope glycoprotein GP2-relatedF: Ebola-like_HR1-HR2ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF01611Filovirus glycoprotein (Filo_glycop)Filovirus glycoprotein- Family
PF22307Envelope glycoprotein GP2-like, HR1-HR2 (Ebola-like_HR1-HR2)Envelope glycoprotein GP2-like, HR1-HR2This entry spans heptad repeats 1 and 2 of the glycoprotein (GP) from Ebola and Marburg viruses [1-5]. Viral infection involves the formation of a trimer-of-hairpins structure (three HR1s helices, buttressed by three HR2 helices lying in antiparallel ...This entry spans heptad repeats 1 and 2 of the glycoprotein (GP) from Ebola and Marburg viruses [1-5]. Viral infection involves the formation of a trimer-of-hairpins structure (three HR1s helices, buttressed by three HR2 helices lying in antiparallel orientation). This domain may have been acquired via horizontal transfer from retroviruses.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Envelope glycoprotein,GP1,Envelope glycoprotein
Envelope glycoprotein