Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyLipoxygenase 8098328 3001410 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyLipase/lipooxygenase domain (PLAT/LH2 domain) 8101094 3001168 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyLipase/lipooxygenase domain (PLAT/LH2 domain) 8101094 3001168 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyLipoxygenase 8098328 3001410 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyLipoxygenase 8098328 3001410 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyLipase/lipooxygenase domain (PLAT/LH2 domain) 8101094 3001168 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyLipoxygenase 8098328 3001410 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyLipase/lipooxygenase domain (PLAT/LH2 domain) 8101094 3001168 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
APLAT,RNAse_Pc_likee6ncfA1 A: beta sandwichesX: jelly-rollH: Lipase/lipooxygenase domain (PLAT/LH2 domain) (From Topology)T: Lipase/lipooxygenase domain (PLAT/LH2 domain)F: PLAT,RNAse_Pc_likeECOD (1.6)
ALipoxygenasee6ncfA2 A: alpha bundlesX: Lipoxygenase (From Topology)H: Lipoxygenase (From Topology)T: LipoxygenaseF: LipoxygenaseECOD (1.6)
BPLAT,RNAse_Pc_likee6ncfB1 A: beta sandwichesX: jelly-rollH: Lipase/lipooxygenase domain (PLAT/LH2 domain) (From Topology)T: Lipase/lipooxygenase domain (PLAT/LH2 domain)F: PLAT,RNAse_Pc_likeECOD (1.6)
BLipoxygenasee6ncfB2 A: alpha bundlesX: Lipoxygenase (From Topology)H: Lipoxygenase (From Topology)T: LipoxygenaseF: LipoxygenaseECOD (1.6)
CPLATe6ncfC1 A: beta sandwichesX: jelly-rollH: Lipase/lipooxygenase domain (PLAT/LH2 domain) (From Topology)T: Lipase/lipooxygenase domain (PLAT/LH2 domain)F: PLATECOD (1.6)
CLipoxygenasee6ncfC2 A: alpha bundlesX: Lipoxygenase (From Topology)H: Lipoxygenase (From Topology)T: LipoxygenaseF: LipoxygenaseECOD (1.6)
DPLATe6ncfD1 A: beta sandwichesX: jelly-rollH: Lipase/lipooxygenase domain (PLAT/LH2 domain) (From Topology)T: Lipase/lipooxygenase domain (PLAT/LH2 domain)F: PLATECOD (1.6)
DLipoxygenasee6ncfD2 A: alpha bundlesX: Lipoxygenase (From Topology)H: Lipoxygenase (From Topology)T: LipoxygenaseF: LipoxygenaseECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C, D
PF00305Lipoxygenase (Lipoxygenase)Lipoxygenase- Domain
A, B, C, D
PF01477PLAT/LH2 domain (PLAT)PLAT/LH2 domainThis domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain bind ...This domain is found in a variety of membrane or lipid associated proteins. It is called the PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology) domain. The known structure of pancreatic lipase shows this domain binds to procolipase Pfam:PF01114, which mediates membrane association. So it appears possible that this domain mediates membrane attachment via other protein binding partners. The structure of this domain is known for many members of the family and is composed of a beta sandwich.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C, D
Arachidonate 5-lipoxygenase