Annotations: 7DFV

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth B]	F_UNCLASSIFIED	e7dfvB3	A: alpha arrays	X: HTH	H: HTH	T: winged	F: F_UNCLASSIFIED	ECOD (1.6)
A [auth B]	F_UNCLASSIFIED	e7dfvB2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: F_UNCLASSIFIED	ECOD (1.6)
A [auth B]	F_UNCLASSIFIED	e7dfvB1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Toll/Interleukin receptor TIR domain (From Topology)	T: Toll/Interleukin receptor TIR domain	F: F_UNCLASSIFIED	ECOD (1.6)
B [auth C]	F_UNCLASSIFIED	e7dfvC3	A: alpha arrays	X: HTH	H: HTH	T: winged	F: F_UNCLASSIFIED	ECOD (1.6)
B [auth C]	F_UNCLASSIFIED	e7dfvC2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: F_UNCLASSIFIED	ECOD (1.6)
B [auth C]	F_UNCLASSIFIED	e7dfvC1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Toll/Interleukin receptor TIR domain (From Topology)	T: Toll/Interleukin receptor TIR domain	F: F_UNCLASSIFIED	ECOD (1.6)
C [auth D]	F_UNCLASSIFIED	e7dfvD3	A: alpha arrays	X: HTH	H: HTH	T: winged	F: F_UNCLASSIFIED	ECOD (1.6)
C [auth D]	F_UNCLASSIFIED	e7dfvD2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: F_UNCLASSIFIED	ECOD (1.6)
C [auth D]	F_UNCLASSIFIED	e7dfvD1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Toll/Interleukin receptor TIR domain (From Topology)	T: Toll/Interleukin receptor TIR domain	F: F_UNCLASSIFIED	ECOD (1.6)
D [auth A]	F_UNCLASSIFIED	e7dfvA3	A: alpha arrays	X: HTH	H: HTH	T: winged	F: F_UNCLASSIFIED	ECOD (1.6)
D [auth A]	F_UNCLASSIFIED	e7dfvA2	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: F_UNCLASSIFIED	ECOD (1.6)
D [auth A]	F_UNCLASSIFIED	e7dfvA1	A: a/b three-layered sandwiches	X: Flavodoxin-like	H: Toll/Interleukin receptor TIR domain (From Topology)	T: Toll/Interleukin receptor TIR domain	F: F_UNCLASSIFIED	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth B], B [auth C], C [auth D], D [auth A]	PF00931	NB-ARC domain (NB-ARC)	NB-ARC domain	-	Domain
A [auth B], B [auth C], C [auth D], D [auth A]	PF01582	TIR domain (TIR)	TIR domain	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth B], B [auth C], C [auth D], D [auth A]	NAD+ hydrolase (NADase)	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding nucleoside phosphate binding ion binding ADP binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding nucleoside phosphate binding ion binding ADP binding purine nucleotide binding organic cyclic compound binding anion binding adenyl nucleotide binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding	cellular response to stimulus regulation of biological process regulation of cellular process response to stimulus signaling biological regulation cellular process signal transduction cell communication defense response response to stress	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth B], B [auth C], C [auth D], D [auth A]	IPR000157	Toll/interleukin-1 receptor homology (TIR) domain	Domain
A [auth B], B [auth C], C [auth D], D [auth A]	IPR045344	C-JID domain	Domain
A [auth B], B [auth C], C [auth D], D [auth A]	IPR042197	Apoptotic protease-activating factors, helical domain	Homologous Superfamily
A [auth B], B [auth C], C [auth D], D [auth A]	IPR036390	Winged helix DNA-binding domain superfamily	Homologous Superfamily
A [auth B], B [auth C], C [auth D], D [auth A]	IPR011713	Leucine-rich repeat 3	Repeat
A [auth B], B [auth C], C [auth D], D [auth A]	IPR032675	Leucine-rich repeat domain superfamily	Homologous Superfamily
A [auth B], B [auth C], C [auth D], D [auth A]	IPR035897	Toll/interleukin-1 receptor homology (TIR) domain superfamily	Homologous Superfamily
A [auth B], B [auth C], C [auth D], D [auth A]	IPR044974	Disease resistance protein, plants	Family
A [auth B], B [auth C], C [auth D], D [auth A]	IPR002182	NB-ARC	Domain
A [auth B], B [auth C], C [auth D], D [auth A]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.