8E77

rystal structure of Pcryo_0616, the aminotransferase required to synthesize UDP-N-acetyl-3-amino-D-glucosaminuronic acid (UDP-GlcNAc3NA), incomplete with its external aldimine reaction intermediate

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ADegT_DnrJ_EryC1e8e77A1 A: a+b two layersX: C-terminal domain in some PLP-dependent transferases (From Topology)H: C-terminal domain in some PLP-dependent transferases (From Topology)T: C-terminal domain in some PLP-dependent transferasesF: DegT_DnrJ_EryC1ECOD (1.6)
AAminotran_5_Ne8e77A2 A: a/b three-layered sandwichesX: PLP-dependent transferases (From Topology)H: PLP-dependent transferases (From Topology)T: PLP-dependent transferasesF: Aminotran_5_NECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF01041DegT/DnrJ/EryC1/StrS aminotransferase family (DegT_DnrJ_EryC1)DegT/DnrJ/EryC1/StrS aminotransferase familyThe members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA Swiss:P72454, StsC Swiss:P77952 and StsS [1]. The aminotransferase activity was demons ...The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA Swiss:P72454, StsC Swiss:P77952 and StsS [1]. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyses the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin [1].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
DegT/DnrJ/EryC1/StrS aminotransferase - -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR015424Pyridoxal phosphate-dependent transferaseHomologous Superfamily
IPR000653DegT/DnrJ/EryC1/StrS aminotransferaseFamily
IPR015421Pyridoxal phosphate-dependent transferase, major domainHomologous Superfamily
IPR015422Pyridoxal phosphate-dependent transferase, small domainHomologous Superfamily