Download MendeleyStructure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate
Bitto, E., Bingman, C.A., Grobosky, C.L.To be published.
4KX3
Structure of murine cytosolic 5'-nucleotidase III complexed with thymidine monophosphate
- PDB DOI: https://doi.org/10.2210/pdb4KX3/pdb
- Classification: HYDROLASE
- Organism(s): Mus musculus
- Expression System: Escherichia coli
- Mutation(s): Yes
- Deposited: 2013-05-24 Released: 2013-06-05
Experimental Data Snapshot
- Method: X-RAY DIFFRACTION
- Resolution: 2.10 Å
- R-Value Free: 0.216
- R-Value Work: 0.153
- R-Value Observed: 0.156
Starting Model: experimental
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This is version 1.1 of the entry. See complete history.
Literature
To be published.
Macromolecules
Find similar proteins by:
(by identity cutoff) | 3D Structure
Entity ID: 1 | |||||
|---|---|---|---|---|---|
| Molecule | Chains | Sequence Length | Organism | Details | Image |
| Cytosolic 5'-nucleotidase 3 | 297 | Mus musculus | Mutation(s): 2 Gene Names: Nt5c3 EC: 3.1.3.5 (PDB Primary Data), 3.1.3.91 (UniProt) |  | |
UniProt & NIH Common Fund Data Resources | |||||
Find proteins for Q9D020 (Mus musculus) Explore Q9D020 Go to UniProtKB: Q9D020 | |||||
IMPC: MGI:1927186 | |||||
Entity Groups | |||||
| Sequence Clusters | 30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity | ||||
| UniProt Group | Q9D020 | ||||
Sequence AnnotationsExpand | |||||
| |||||
Small Molecules
| Ligands 5 Unique | |||||
|---|---|---|---|---|---|
| ID | Chains | Name / Formula / InChI Key | 2D Diagram | 3D Interactions | |
| DT Query on DT | B [auth A] | THYMIDINE-5'-MONOPHOSPHATE C10 H15 N2 O8 P GYOZYWVXFNDGLU-XLPZGREQSA-N |  | ||
| EPE Query on EPE | I [auth A] | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID C8 H18 N2 O4 S JKMHFZQWWAIEOD-UHFFFAOYSA-N |  | ||
| BME Query on BME | G [auth A], H [auth A] | BETA-MERCAPTOETHANOL C2 H6 O S DGVVWUTYPXICAM-UHFFFAOYSA-N |  | ||
| EDO Query on EDO | D [auth A], E [auth A], F [auth A], J [auth A] | 1,2-ETHANEDIOL C2 H6 O2 LYCAIKOWRPUZTN-UHFFFAOYSA-N |  | ||
| MG Query on MG | C [auth A] | MAGNESIUM ION Mg JLVVSXFLKOJNIY-UHFFFAOYSA-N |  | ||
Experimental Data & Validation
Experimental Data
- Method: X-RAY DIFFRACTION
- Resolution: 2.10 Å
- R-Value Free: 0.216
- R-Value Work: 0.153
- R-Value Observed: 0.156
- Space Group: P 43 2 2
Unit Cell:
| Length ( Å ) | Angle ( ˚ ) |
|---|---|
| a = 46.872 | α = 90 |
| b = 46.872 | β = 90 |
| c = 285.873 | γ = 90 |
| Software Name | Purpose |
|---|---|
| DENZO | data reduction |
| SCALEPACK | data scaling |
| MOLREP | phasing |
| REFMAC | refinement |
| PDB_EXTRACT | data extraction |
| HKL-3000 | data collection |
Entry History
Deposition Data
- Released Date: 2013-06-05 Deposition Author(s): Bitto, E., Bingman, C.A., Grobosky, C.L.
Revision History (Full details and data files)
- Version 1.0: 2013-06-05
Type: Initial release - Version 1.1: 2023-09-20
Changes: Data collection, Database references, Derived calculations, Refinement description
