5TSX

Classification: VIRAL PROTEIN
Organism(s): Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE), Homo sapiens
Expression System: Escherichia coli BL21(DE3)
Mutation(s): Yes

Deposited: 2016-10-31 Released: 2017-11-08
Deposition Author(s): Skorupka, K., Ganser-Pornillos, B.K., Pornillos, O.
Funding Organization(s): National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID), National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)

Experimental Data Snapshot

Starting Model: experimental
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wwPDB Validation 3D Report Full Report

Ligand Structure Quality Assessment

This is version 1.3 of the entry. See complete history.

Literature

Macromolecule Content

Macromolecules

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(by identity cutoff) | 3D Structure

Entity ID: 1
Molecule	Chains	Sequence Length	Organism	Details	Image
HIV-1 CA protein	A, B, C, D, E A, B, C, D, E, F, G, H, I, J, K, L	231	Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)	Mutation(s): 4 Gene Names: gag
UniProt
Find proteins for P12493 (Human immunodeficiency virus type 1 group M subtype B (isolate NY5)) Explore P12493 Go to UniProtKB: P12493
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P12493
Sequence Annotations Expand
Reference Sequence

Find similar proteins by: Sequence | 3D Structure

Entity ID: 2
Molecule	Chains	Sequence Length	Organism	Details	Image
Nuclear pore complex protein Nup153	M N O P Q [auth R] M, N, O, P, Q [auth R], R [auth T]	23	Homo sapiens	Mutation(s): 0
UniProt & NIH Common Fund Data Resources
Find proteins for P49790 (Homo sapiens) Explore P49790 Go to UniProtKB: P49790
PHAROS: P49790 GTEx: ENSG00000124789
Entity Groups
Sequence Clusters	30% Identity50% Identity70% Identity90% Identity95% Identity100% Identity
UniProt Group	P49790
Sequence Annotations Expand
Reference Sequence

Small Molecules

Ligands 1 Unique
ID	Chains	Name / Formula / InChI Key	2D Diagram	3D Interactions
FLU Query on FLU Download Ideal Coordinates CCD File SDF format, chain S [auth A] SDF format, chain T [auth B] SDF format, chain U [auth G] SDF format, chain V [auth H] MOL2 format, chain S [auth A] MOL2 format, chain T [auth B] MOL2 format, chain U [auth G] MOL2 format, chain V [auth H] mmCIF format, chain S [auth A] mmCIF format, chain T [auth B] mmCIF format, chain U [auth G] mmCIF format, chain V [auth H]	S [auth A], T [auth B], U [auth G], V [auth H]	2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID C₂₀ H₁₂ O₅ YKGGGCXBWXHKIZ-UHFFFAOYSA-N		Interactions Focus chain S [auth A] Focus chain T [auth B] Focus chain U [auth G] Focus chain V [auth H] Interactions & Density Focus chain S [auth A] Focus chain T [auth B] Focus chain U [auth G] Focus chain V [auth H]

Experimental Data & Validation

Unit Cell:

Software Package:

Entry History & Funding Information

Deposition Author(s):

Skorupka, K.

Funding Organization	Location	Grant Number
National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)	United States	R01-AI120956
National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)	United States	P50-GM103297

Version 1.0: 2017-11-08
Type: Initial release
Version 1.1: 2019-12-11
Changes: Author supporting evidence, Database references
Version 1.2: 2023-10-04
Changes: Data collection, Database references, Refinement description
Version 1.3: 2024-11-06
Changes: Structure summary