News

Undergrads/Grads: January 2024 Science Communication Boot Camp (Cancelled)

09/25 PDB101 News

The 2024 Boot Camp has been cancelled.

Imatinib blocks the ATP-binding site of the c-Abl kinase domain, stopping its action. Several regions in the kinase are important for its function and inhibition by imatinib, as seen in structures of the kinase with ADP (PDB ID <a href="https://www.rcsb.org/structure/2g2i">2g2i</a>) and with imatinib (PDB ID <a href="https://www.rcsb.org/structure/2hyy">2hyy</a>). The “activation loop” closes over the active site and controls access, and is regulated by a tyrosine that may be phosphorylated. The “gatekeeper” threonine, the “DFG Motif”, and several hydrogen bonding amino acids (not shown) are involved in specific interactions with imatinib, helping make the drug more selective. From the Molecule of the Month on <a href="https://pdb101.rcsb.org/motm/283">c-Abl Protein Kinase and Imatinib</a>.Imatinib blocks the ATP-binding site of the c-Abl kinase domain, stopping its action. Several regions in the kinase are important for its function and inhibition by imatinib, as seen in structures of the kinase with ADP (PDB ID 2g2i) and with imatinib (PDB ID 2hyy). The “activation loop” closes over the active site and controls access, and is regulated by a tyrosine that may be phosphorylated. The “gatekeeper” threonine, the “DFG Motif”, and several hydrogen bonding amino acids (not shown) are involved in specific interactions with imatinib, helping make the drug more selective. From the Molecule of the Month on c-Abl Protein Kinase and Imatinib.

RCSB PDB and the Rutgers Institute for Quantitative Biomedicine will host a virtual boot camp with a focus on Science Communication in Biology and Medicine. Students will develop writing and 3D molecular visualization skills by collaborating on articles that will be published at PDB-101.

The boot camp will run from 9:30am - 4:30pm ET during January 8-12, 2024.

Undergraduates and and graduate students interested in science writing/visualization/communications for biology and medicine should apply to [email protected] by October 31 with

  • a brief statement of interest (100 words)
  • resume
  • an unofficial transcript
  • science writing sample (from coursework or a published paper that exemplifies your work)

This boot camp is a 1-credit pass/fail course at Rutgers University. A limited number of scholarships for visiting scholars are available.

Visit the Institute for Quantitative Biomedicine for additional details.

News Index