Explore Mechanism and Catalytic Site Annotations

03/31 

From the Annotations tab, select the Explore in 3D option to view in Mol*

Data on catalytically active residues from the Mechanism and Catalytic Site Atlas (M-CSA) have been mapped to >1000 PDB structures at RCSB.org.

From the Annotations tab for these entries

• access M-CSA data annotations (example)
• visualize active sites using Mol* (example)
• launch a structure motif search to find these active sites in other experimentally-determined PDB structures and in Computed Structure Models (CSMs; example)

Advanced Search: Structure Motif can be used to identify all structures with M-CSA annotations. User guide documentation is available.

Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites.
Ribeiro AJM et al. (2017) Nucleic Acids Res: 46, D618-D623. DOI: 10.1093/nar/gkx1012

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